Asia Ventilation Forum
The Asia Ventilation Forum (AVF) is a not-for-profit organisation comprising members from different Asian countries. We share our knowledge and experience in respiratory care and critical care with intensive care unit (ICU) workers across the continent with the aim of improving care and outcomes for the critically ill. There are two AVF Podcast series. "Behind-The-Scenes ICU Stories" invites colleagues to share anything and everything on their personal experiences. Expect heart-to-heart discussions on topics that may or may not have been widely described in the medical literature. "The Challenges of Airway Management During the Pandemic" invites colleagues to share anything and everything on how they deal with various clinical situations. Expect discussions on how experts personalise evidence-based medicine for the patient at the bedside. These Podcasts are hosted by Dr Jason Phua, respiratory physician and intensivist at Alexandra Hospital, National University Health System, Singapore, and Dr Jose Emmanuel Palo, intensivist at The Medical City, the Philippines.
Asia Ventilation Forum
Every Deep-Drawn Breath: Professor Wes Ely
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Season 1
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Episode 7
In this AVF Podcast: Behind-The-Scenes ICU Stories episode, Professor Wes Ely (@WesElyMD) talks about his recently published book on healing, recovery, and transforming medicine in the intensive care unit (ICU): Every Deep-Drawn Breath (#EveryDeepDrawnBreath, #EDDB). Professor Ely is a pulmonary and critical care physician-scientist and serves as the Grant W. Liddle Endowed Chair in medicine at Vanderbilt University Medical Center. He is the associate director of ageing research for the Tennessee Valley Veterans Affairs Geriatric Research Education Clinical Center (GRECC). He is also the founder and codirector of the Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center.
Issues discussed in this interview:
- The impact of delirium and post-intensive care syndrome on ICU patients and their families
- The science behind the prevention, detection, and management of delirium in the ICU
- The ABCDEF bundle and the COVID-19 pandemic
- Real life stories of persons with delirium and post-intensive care syndrome
- Bringing humanity back to medicine, one person at a time
Work cited:
- Ely W. Every deep drawn breath. New York, US: Scribner, 2021.
- Critical Illness, Brain Dysfunction, and Survivorship (CIBS) Center (https://www.icudelirium.org/).
- Ely EW, Baker AM, Dunagan DP, et al. Effect on the duration of mechanical ventilation of identifying patients capable of breathing spontaneously. N Engl J Med 1996;335:1864-9.
- Needham DM, Davidson J, Cohen H, et al. Improving long-term outcomes after discharge from intensive care unit: report from a stakeholders' conference. Crit Care Med 2012;40:502-9.
- Ely EW, Inouye SK, Bernard GR, et al. Delirium in mechanically ventilated patients: validity and reliability of the confusion assessment method for the intensive care unit (CAM-ICU). JAMA 2001;286:2703-10.
- Ely EW, Truman B, Shintani A, et al. Monitoring sedation status over time in ICU patients: reliability and validity of the Richmond Agitation-Sedation Scale (RASS). JAMA 2003;289:2983-91.
- Ely EW, Shintani A, Truman B, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA 2004;291:1753-62.
- Pandharipande PP, Pun BT, Herr DL, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA 2007;298:2644-53.
- Riker RR, Shehabi Y, Bokesch PM, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients: a randomized trial. JAMA 2009;301:489-99.
- Hughes CG, Mailloux PT, Devlin JW, et al. Dexmedetomidine or propofol for sedation in mechanically ventilated adults with sepsis. N Engl J Med 2021;384:1424-36.
- Girard TD, Kress JP, Fuchs BD, et al. Efficacy and safety of a paired sedation and ventilator weaning protocol for mechanically ventilated patients in intensive care (Awakening and Breathing Controlled trial): a randomised controlled trial. Lancet 2008;371:126-34.
- Pandharipande PP, Girard TD, Jackson JC, et al. Long-term cognitive impairment after critical illness. N Engl J Med 2013;369:1306-16.
- Pun BT, Balas MC, Barnes-Daly MA, et al. Caring for critically ill patients with the ABCDEF bundle: results of the ICU Liberation Collaborative in over 15,000 adults. Crit Care Med 2019;47:3-14.
- Girard TD, Exline MC, Carson SS, et al. Haloperidol and ziprasidone for treatment of delirium in critical illness. N Engl J Med 2018;379:2506-16.
- Liu K, Nakamura K, Katsukawa H, et al. Implementation of the ABCDEF bundle for critically ill ICU patients during the COVID-19 pandemic: a multi-national 1-day point prevalence study. Front Med (Lausanne) 2021;8:735860.